20 November 2019
In a new study published in Nature Communications, Manchester Breast Centre scientists Rob Clarke and Rachel Eyre demonstrate that NHS arthritis drugs anakinra, canakinumab and sulfasalazine could in future be repurposed to help treat breast cancer, following the discovery of the role of bone marrow in the spread of the disease to the bone.
Also covered in the Sun, BBC regional TV news, BBC Radio Manchester, BBC Radio Scotland
27 January 2020
New laboratory research has found that a drug based on a natural compound found in broccoli, kale and other cruciferous vegetables could reverse or even prevent breast cancer becoming resistant to hormone therapy.
Rob Clarke, Bruno Simoes and Sacha Howell from Manchester Breast Centre found that the new drug, SFX-01, blocks an important chain of reactions in breast cancer cells. In future, it could be added to hormone therapies to boost their effectiveness.