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Selected Publications from 2019

Publications


Patient-Reported Outcomes Over 5 Years After Whole- or Partial-Breast Radiotherapy: Longitudinal Analysis of the IMPORT LOW (CRUK/06/003) Phase III Randomized Controlled Trial
Bhattacharya IS, Haviland JS, Kirby AM, Kirwan CC, Hopwood P, Yarnold JR, Bliss JM, Coles CE; IMPORT Trialists
Journal of Clinical Oncology   2019  37:4  305-371
 
IBIS-II investigators Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial
Cuzick J, Sestak I, Forbes JF, Dowsett M, Cawthorn S, Mansel RE, Loibl S, Bonanni B, Evans DG, Howell A
Lancet. 2019 Dec 11. pii: S0140-6736(19)32955-1  2019   
 
6 versus 12 months of adjuvant trastuzumab for HER2-positive early breast cancer (PERSEPHONE): 4-year disease-free survival results of a randomised phase 3 non-inferiority trial.
Earl HM, Hiller L, Vallier AL, Loi S, McAdam K, Hughes-Davies L, Harnett AN, Ah-See ML, Simcock R, Rea D, Raj S, Woodings P, Harries M, Howe D, Raynes K, Higgins HB, Wilcox M, Plummer C, Mansi J, Gounaris I, Mahler-Araujo B, Provenzano E, Chhabra A, Abraham JE, Caldas C, Hall PS, McCabe C, Hulme C, Miles D, Wardley AM, Cameron DA, Dunn JA;.PERSEPHONE Steering Committee and Trial Investigators.
Lancet  2019  393(10191)  2599-2612
 
Breast cancer pathology and stage are better predicted by risk stratification models that include mammographic density and common genetic variants
Evans DGR, Harkness EF, ..Howell SJ, Maxwell AJ, Howell A,… Newman WG, Cuzick J.
Breast Cancer Res Treat. 2019 Apr 2. doi: 10.1007/s10549-019-05210-2.   2019   
 
Microenvironmental IL1ß promotes metastatic colonisation of breast cancer cells in the bone via activation of Wnt
Eyre R, Alférez DG, Santiago-Gómez A, Spence K, McConnell JC, Hart C, Simões BM, Lefley D, Tulotta C, Storer J, Gurney A, Clarke N, Brown MD, Howell SJ, Sims AH, Farnie G, Ottewell PD and Clarke RB
Nature Communications. 2019 Nov 1;10(1):5016. doi: 10.1038/s41467-019-12807-0  2019   
 
The effectiveness of home versus community-based weight control programmes initiated soon after breast cancer diagnosis: a randomised controlled trial
Harvie M, Pegington M, McMullan D, Morris J, Howell S, Howell A.
Br J Cancer. 2019 Sep;121(6):443-454. doi: 10.1038/s41416-019-0522-6  2019   
 
Prediction of reader estimates of mammographic density using convolutional neural networks
Ionescu GV, Fergie M, Brentnall AR, Cuzick J, Evans DG, Astley SM.
J Med Imaging (Bellingham) 2019 Jul;6(3):031405. doi:10.1117/1.JMI.6.3.03140  2019   
 
Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study
Rothwell DG, Ayub M, Cook N, Thistlethwaite F, Carter L, Dean E, Smith N, Villa S, Dransfield J, Clipson A, White D, Nessa K, Ferdous S, Howell M, Gupta A, Kilerci B, Mohan S, Frese K, Gulati S, Miller C, Jordan A, Eaton H, Hickson N, O'Brien C, Graham D, Kelly C, Aruketty S, Metcalf R, Chiramel J, Tinsley N, Vickers AJ, Kurup R, Frost H, Stevenson J, Southam S, Landers D, Wallace A, Marais R, Hughes AM, Brady G, Dive C, Krebs. MG.
Nature Medicine  2019  25(5)  738-743
 


Seminars


Date:  11 May 202115:30
Speaker:  Shelley Potter
From:  University of Bristol and the Bristol Breast Care Centre at North Bristol NHS Trust
Title:  TBC
Host:  Cliona Kirwan
 
Date:  15 June 202109:00
Speaker:  Kara Britt
From:  Peter MacCallum Cancer Centre, Victoria Australia
Title:  TBC
Host:  Sacha Howell
 
Date:  20 July 202109:00
Speaker:  Bruce Mann & Belinda Parker
From:  Melbourne, Australia
Title:  TBC
Host:  Rajiv Dave