Selected Publications from 2018


A comparison of five methods of measuring mammographic density: a case-control study.
Astley, Susan; Harkness, Elaine; Sergeant, Jamie; Warwick, Jane; Stavrinos, Paula; Warren, Ruth; Wilson, Mary; Beetles, Ursula; Gadde, Soujanya; Lim, Yit; Jain, Anil; Bundred, Sara; Barr, Nicola; Reece, Valerie; Brentnalll, Adam R.; Cuzick, Jack; Howell, Anthony; Evans, D. Gareth.
Breast Cancer Research  2018  20(1)  10
PERSEPHONE: 6 versus 12 months (m) of adjuvant trastuzumab in patients (pts) with HER2 positive (+) early breast cancer (EBC): Randomised phase 3 non-inferiority trial with definitive 4-year (yr) disease-free survival (DFS) results.
Earl, Helena Margaret; Hiller, Louise; Vallier, Ann-Laure; Shrushma, Loi; Howe, Donna; Higgins, Helen B; McAdam, Karen; Hughes-Davies, Luke; Harnett, Adrian Nigel; Ah-See, Mei-Lin; Simcock, Richard; Rea, Daniel William; Mansi, Janine; Abraham, Jean; Caldas, Carlos; Hulme, Claire; Miles, David; Wardley, Andrew M; Cameron, David A.; Dunn, Janet.
Journal of Clinical Oncology  2018  36, no. 15_suppl   506
Breast cancer risk in a screening cohort of Asian and white British/Irish women from Manchester UK.
Evans, DG; Brentnall, AR; Harvie, M; Astley, S; Harkness, EF, Stavrinos, P; Donnelly; LS; Sampson, S; Idries, F; Watterson, D; Cuzick, J; Wilson, M; Jain, A; Harrison, F; Maxwell, AJ; Howell, A.
BMC Public Health   2018  18(1)  178
Personalized prevention in high risk individuals: Managing hormones and beyond.
Evans, DG; Howell, SJ; Howell, S.
Breast  2018  39  139-147.
RAZOR: A Phase II Open Randomized Trial of Screening Plus Goserelin and Raloxifene Versus Screening Alone in Premenopausal Women at Increased Risk of Breast Cancer.
Howell, Anthony; Ashcroft, Linda; Fallowfield, Lesley; Eccles Diana M; Eeles, Rosalind A.; Ward, Ann; Brentnall, Adam R; Dowsett, Mitchell; Cuzick, Jack; Greenhalgh, Rosemary; Boggis, Caroline; Motion, Jamie; Sergeant, Jamie; Adams, Judith; Evans, Dafydd.
Cancer Epidemiology, Biomarkers & Prevention  2018  27(1)  58-66
Ethnicity influences breast cancer stem cells’ drug resistance.
Kamal, M; Nafie, EHO; Elsers, S; Alanwar, S; Ibrahim, R; Farag, F; Mlees, M; Simões, BM; Spence, K; Santiago-Gomez, A; Salem, ML; Clarke, RB.
The Breast Journal  2018  24(4)  701-703
Risk-reducing mastectomy rates in the US: a closer examination of the Angelina Jolie effect.
Liede, A; Cai, M; Crouter, TF; Niepel, D; Callaghan, F; Evans, DG.
Breast Cancer Res. Treat.   2018  171(2)  435-442
Integrin-Rac signalling for mammary epithelial stem cell self-renewal
Olabi, S; Ucar, A; Brennan, K, Streuli, CH.
Breast Cancer Research   2018  33(7-8)   852-857
Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP.
Piggott, L. Silva, A; Robinson, T; Santiago-Gómez , A; Simões, BM; Becker, M, Fichtner, I; Andera, L; Young, P; Morris, C; Barrett-Lee, P; Alchami, F; Piva, M; Vivanco, MD; Clarke, RB; Gee, J; Clarkson, R;
Clinical Cancer Research  2018  24(10)  2452-2463
Estrogenicity of essential oils is not required to relieve symptoms of urogenital atrophy in breast cancer survivors.
Simões B, Kohler B; Clarke RB; Stringer J; Novak-Frazer L; Young K; Rautemaa-Richardson R; Zucchini G; Armstrong A; Howell SJ.
Therapeutic Advances in Medical Oncology  2018  10 
Carboplatin in BRCA1/2-mutated and triple-negative breast cancer BRCAness subgroups: the TNT Trial.
Tutt, A; Tovey, H; Cheang, MCU; Kernaghan, S; Kilburn, L; Gazinska, P; Owen, J; Abraham, J; Barrett, S; Barrett-Lee, P; Brown, R; Chan, S; Dowsett, M; Flanagan, JM; Fox, L; Grigoriadis, A; Gutin, A; Harper-Wynne, C; Hatton, MQ; Hoadley, KA; Parikh, J; Parker, P; Perou, CM; Roylance, R; Shah, V; Shaw, A; Smith, IE; Timms, KM; Wardley, AM; Wilson, G; Gillett, C; Lanchbury, JS; Ashworth, A; Rahman, N; Harries, M; Ellis, P; Pinder, SE, Bliss, JM.
Nature Medicine  2018  24(5)  628-637
Use of Single-Nucleotide Polymorphisms and Mammographic Density Plus Classic Risk Factors for Breast Cancer Risk Prediction.
Van Veen, Elke; Brentnall, Adam R; Byers Helen; Harkness, Elaine; Astley, Susan; Sampson, Sarah; Howell, Anthony; Newman, William; Cuzick, Jack; Evans, Dafydd.
JAMA Oncology   2018  4(4)  476-482
Epithelial and stromal circadian clocks are inversely regulated by their mechano-matrix environment.
Williams, J; Yang, N; Wood, A; Zindy, E; Meng, QJ; Streuli, CH.
Journal of Cell Science   2018  131(5) 
Penetrance estimates for BRCA1, BRCA2 (also applied to Lynch syndrome) based on presymptomatic testing: a new unbiased method to assess risk?
Woodward, Emma; Harkness, Elaine; Howell, Anthony; Plaskocinska, I; Maher, Eamonn, R; Tischkowitz, Marc D; Lalloo, Fiona.
Journal of Medical Genetics  2018  55(7)  442-448


Date:  24 May 202415:00
Speaker:  Dr Gerald Lip
From:  NHS Grampian & University of Aberdeen
Title:  AI in breast cancer screening - are we there yet?
Host:  Sue Astley
Date:  18 July 202400:00
Speaker:  Andrea Morandi
From:  University of Florence, Italy
Title:  TBC
Host:  Rob Clarke
Date:  18 July 202400:00
Speaker:  Ernestina De Francesco
From:  Universities of Catania and Enna, Italy
Title:  TBC
Host:  Rob Clarke