Prevent Breast Cancer
Patient and Public Participation
Selected Publications - 2023
Selected Publications - 2022
Selected Publications - 2021
Selected Publications - 2020
Selected Publications - 2019
Selected Publications - 2018
Selected Publications - 2017
Selected Publications - 2016
Public Outreach Event 2020
IPVC Research Open Day
Annual Symposium 2016
The University of Manchester
Christie NHS Foundation Trust
Prevent Breast Cancer
Manchester University NHS Foundation Trust (MFT)
Breast Cancer Now
News items from 2023
Manchester research into understanding how breast cancer starts
12 Oct 2023
Manchester is a key player in the monumental effort to progress research into both the prediction and prevention of breast cancer. In the first of a new series of blogs, created by Prevent Breast Cancer, Dr Andrew Gilmore explains what breast cancer actually is and how Manchester research is trying to understand what causes breast cancer and to stop it in its tracks.
Manchester scientists investigate how to stop triple negative breast cancer spreading
11 Oct 2023
Dr Sankari Nagarajan and her team have been awarded £249,992 from Breast Cancer Now to help discover why some triple-negative breast cancers spread to other parts of the body and whether existing drugs can be repurposed to stop this from happening.
Study improves accuracy of predictive breast cancer genetic test for Ashkenazi Jewish women
03 Jul 2023
Manchester researchers have developed a way to improve the accuracy of breast cancer genetic testing for women from Ashkenazi Jewish backgrounds.
Festschrift Meeting: A celebration of Professor Tony Howell’s academic achievements
03 Jul 2023
On Friday 30th June, Manchester Breast Centre (MBC) hosted a Festschrift Meeting at the Oglesby Cancer Research Building to celebrate Professor Tony Howell’s academic achievements.
Sarah Harding legacy research project recruits first participant
27 Jun 2023
A pioneering cancer research project launched in memory of singer Sarah Harding, and made possible through funding from The Christie Charity Sarah Harding Breast Cancer Appeal and Cancer Research UK, has recruited its first participant.
The Christie Paterson cancer research centre completes
22 May 2023
Following a devastating fire which caused significant damage to the Paterson cancer research facility in 2017, building work on the new Paterson building at The Christie NHS Foundation Trust in Manchester has completed.
Targeting variant of common protein may dramatically boost effectiveness of breast cancer treatment
05 Jan 2023
A rare variant of a protein present in nearly all human cells may hold the key to improving the effectiveness of breast cancer treatment, according to University of Manchester research funded by Breast Cancer Now. This discovery, published today (5 January 2023) in Oncogene, is the first time scientists have identified that targeting RAC1B, a variant of the RAC1 protein, could be a potential way of improving treatment for breast cancer.
News items from 2022
Aged under 35? Testers needed to trial a new app
23 Nov 2022
An exciting study, led by Mary Pegington, a Breast Cancer Research Dietitian, is looking for volunteers to trial a new app.
One in Two podcast -"Breast Cancer with Professor Gareth Evans: Should all women be screened equally?"
03 Oct 2022
One in Two: A Manchester Cancer Research Podcast. In this episode we speak to Professor Gareth Evans about the importance of breast cancer screening, as well as the risk predictors of breast cancer as he answers the question: Should all women be screened equally for breast cancer?
Guidelines on breast cancer surgery need revision, find researchers
22 Sep 2022
Current international breast cancer surgery guidelines need urgent revision, according to a meta-analysis of 68 studies comprising 112,140 patients by University of Manchester researchers.
Father and son doctors provide care for the same patient for over 4 decades
18 Jul 2022
A Tameside pensioner, who has been diagnosed with 5 different types of cancer in the past 35 years, has paid tribute to the doctors and researchers who have given her hope, including father and son consultants Tony and Sacha Howell.
Case study: Unravelling breast cancer metastasis in the lab
01 Jul 2022
Dr Hannah Harrison uses a novel cell culture system to reveal how breast cancer creates perfect conditions for it to spread in the body – and how we can stop this from happening.
24 May 2022
PROCAS 2 launched in 2017 with a key aim to assess the feasibility of implementing a breast cancer risk stratification programme into a routine NHS setting. We talk to Prof. David French about his research into the effects of embedding such a programme.
MFT Cancer Professor features in Julia Bradbury breast cancer documentary
28 Apr 2022
Professor Gareth Evans features in a documentary following TV presenter Julia Bradbury’s personal breast cancer journey, where he discusses risk factors, genetic testing and SNPs to help Julia understand her cancer risk.
Aiding Breast Cancer Prevention in Under-supported Groups
20 Apr 2022
University of Manchester Research IT Mobile Development Service have been working with research dietician, Mary Pegington at The Nightingale Centre, Wythenshawe Hospital on an app which targets women under the age of 35 with a family history of breast cancer – a group for whom there is little support at present.
News items from 2021
Dr Chiara Francavilla, Wellcome Trust Sir Henry Dale Research Fellow
20 Oct 2021
Congratulations to Dr Chiara Francavilla, who has been awarded an extension to her Wellcome Trust Sir Henry Dale Research Fellowship.
Aspirin may help treat aggressive breast cancer
18 Aug 2021
Aspirin may help fight aggressive breast cancer by making hard-to-treat tumours more responsive to anti-cancer drugs, doctors say. A team at the Christie NHS Foundation Trust, in Manchester, are beginning a trial with triple-negative breast-cancer patients.
Early breast cancer care largely safe and effective in pandemic
29 Mar 2021
A UK-wide study involving patients with early breast cancer has shown their care was no less safe and effective than before the pandemic started.
Archived News Items
New study on anastrazole treatment which reduces risk of breast cancer
13 Dec 2019
Ground-breaking research has found that the drug, anastrozole, continues to reduce the risk of breast cancer, even 10 years after initial treatment.
Drugs commonly used to treat arthritis may help to prevent breast cancer spreading to the bone, where it is incurable.
20 Nov 2019
In a new study published in Nature Communications, Manchester Breast Centre scientists Rob Clarke and Rachel Eyre demonstrate that NHS arthritis drugs anakinra, canakinumab and sulfasalazine could in future be repurposed to help treat breast cancer, following the discovery of the role of bone marrow in the spread of the disease to the bone.
Elke van Veen: Postgraduate Student of the Year
02 Jul 2019
Elke van Veen has won the prestigious Postgraduate Student of the Year award at this year’s Manchester Doctoral Excellence Awards.
PROCAS: revolutionising the breast screening process
11 Jun 2019
Women who are screened for breast cancer will receive greater tailored preventative intervention following the advancements of Prevent Breast Cancer’s PROCAS study, led by Professor Gareth Evans.
New research improves risk prediction, prevention and treatment of breast cancer
08 Jun 2019
Women screened for breast cancer could be given greater information on how likely they are to develop breast cancer, possible treatments to reduce their risk, and if it did develop, how likely it will respond to different treatments, according to new research.
Manchester team plays major part in pioneering research into breast cancer treatment
05 Jun 2019
Study reveals combining standard treatment with investigational therapy may extend life by up to six months.
Researchers identify a novel type of genetic change resulting in inherited breast cancer
03 Aug 2018
Researchers from the NIHR Manchester Biomedical Research Centre have identified a new mechanism which switches off a gene in families affected by breast and ovarian cancer.
Genetic test could give women a more accurate breast cancer risk when combined with standard screening
25 Jan 2018
New Manchester-led research shows a promising genetic test, when combined with mammograms, could provide a more accurate breast cancer risk in women attending routine breast cancer screening.
Manchester scientists given funding to research how to stop breast cancer spreading to bone
13 Oct 2017
University of Manchester scientist Dr Robert Clarke was given the grant by Breast Cancer Now on Secondary Breast Cancer Awareness Day and will use the grant of more than £195,000 for his research on breast cancer stem cells (BCSCs)
New test set to transform breast cancer prevention
09 Oct 2017
Women who have a family history of breast cancer are set to benefit from a new genetic test at Manchester University NHS Foundation Trust
Manchester scientist to study how ‘hibernating’ breast cancer cells evade treatment
12 Jul 2017
A leading Manchester scientist has been awarded a grant worth over £185,000 by Breast Cancer Now to investigate how breast cancer cells are able to hibernate for years before returning elsewhere in the body.
Inbuilt Body Clocks Link Breast Stiffness to Cancer Risks
31 Jan 2017
University of Manchester biologists have discovered that breast tissues have 24-hour body clocks, and that several hundred genes are regulated in a daily cycle.
University of Manchester Minute Lectures Series
04 Jul 2016
Take a look at the work being done in our Manchester Breast Centre affiliated labs
Could 5:2 diet play a role in preventing breast cancer?
17 Jun 2016
"Women who follow the 5:2 diet 'could reduce their risk of breast cancer','' the Mail Online reports.
Artist joins forces with Manchester Breast Centre to create new project to support breast cancer
08 Apr 2016
A Wilmslow artist has created a new project which she hopes will empower those battling breast cancer.
Combination of lapatinib and trastuzumab shrinks HER2 positive breast cancer significantly in 11 days after diagnosis
11 Mar 2016
Approximately a quarter of women with HER2 positive breast cancer, who were treated with a combination of the targeted drugs lapatinib and trastuzumab before surgery and chemotherapy, saw their tumours shrink significantly or even disappear, according to results from a Manchester-led trial.
Delving deeper into breast density
03 Mar 2016
Researchers in Manchester have been exploring the causes of high breast density – a known risk factor for breast cancer – that could reveal new ways to prevent the disease.
Breast screening recommendation for women with cancer-causing syndrome
07 Dec 2015
Researchers in Manchester have found that women with an inherited genetic syndrome are at increased risk of developing breast cancer and should be considered for earlier screening.
Manchester breast cancer clinic attributes increased uptake of double mastectomies to Angelina Jolie effect
24 Nov 2015
Researchers at a breast cancer prevention clinic in Manchester have observed an increased uptake of preventative double mastectomies since May 2013, when Angelina Jolie announced that she had undergone the procedure.
Cancer scientist appointed by President Obama visits Manchester
24 Oct 2015
Professor Max Wicha a leading breast cancer specialist from the University of Michigan, has been at The University of Manchester to discuss collaborations and deliver a keynote address to scientists.
Developing a gel that mimics human breast for cancer research
07 Oct 2015
Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and reduce animal testing.
New approach found to tackle breast cancer hormone therapy resistance
17 Sep 2015
University of Manchester researchers funded by Breast Cancer Now have discovered a new explanation as to why women with oestrogen receptor positive (ER+) breast cancer develop resistance to hormone treatment, and a potential new approach to overcome the problem.
New drug combination shows promise for breaking breast cancer resistance
20 Apr 2015
Researchers from The University of Manchester working with drug development company Evgen Pharma, have developed a new combination of drugs which could overcome treatment resistance and relapse in breast cancer.
Potential for prediction of progression for early form of breast cancer
15 Apr 2015
Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.
Researchers identify new ways to drain cancer’s ‘fuel tank’
25 Nov 2014
Scientists at The University of Manchester have discovered a potential weakness in cancer’s ability to return or become resistant to treatment, by targeting the ‘fuel’ part of stem cells which allows tumours to grow.
15 February 2024
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