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Selected Publications - 2020
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Breast Cancer Now
News items from 2021
Aspirin may help treat aggressive breast cancer
18 Aug 2021
Aspirin may help fight aggressive breast cancer by making hard-to-treat tumours more responsive to anti-cancer drugs, doctors say. A team at the Christie NHS Foundation Trust, in Manchester, are beginning a trial with triple-negative breast-cancer patients.
Early breast cancer care largely safe and effective in pandemic
29 Mar 2021
A UK-wide study involving patients with early breast cancer has shown their care was no less safe and effective than before the pandemic started.
News items from 2020
But….what about secondary breast cancer?
23 Oct 2020
In this blog written for Breast Cancer Awareness month, Dr Angelica Santiago Gomez, a Postdoctoral Researcher in Professor Rob Clarke’s lab, talks about her research in secondary breast cancer.
Manchester cancer professor receives honour from Royal College of Obstetricians and Gynaecologists
21 Oct 2020
Manchester cancer researcher Professor Gareth Evans was recently recognised for his work in advancing women’s health, after receiving a prestigious honorary fellowship by the Royal College of Obstetricians and Gynaecologists.
Drug target for aggressive breast cancer found
27 Jul 2020
A team of British and American scientists have discovered a way to slow the growth of breast cancer stem cells in the lab. The study led by Dr Bruno Simões and Professor Rob Clarke from The University of Manchester could eventually lead to combination drug therapies on previously untreatable breast cancers.
Scientists stop breast cancer cells from spreading in the lab
13 Feb 2020
Biologists have discovered a way to stop cells from one of the most aggressive types of breast cancer spreading in the lab. The results of the study of Triple-Negative Breast Cancer by the team from the Universities of Manchester, Glasgow and Sheffield and funded by Breast Cancer Now are published in Oncogene.
Dr Rachel Eyre awarded the 2019 Sir Antony Driver Prize
03 Feb 2020
Dr Rachel Eyre has been awarded the 2019 Sir Antony Driver Prize which is awarded each year to a Breast Cancer Now researcher who has shown an incredible commitment to their field of research.
Novel drug inspired by cruciferous vegetables could reverse drug resistance in oestrogen receptor positive breast cancer
27 Jan 2020
New laboratory research has found that a drug based on a natural compound found in broccoli, kale and other cruciferous vegetables could reverse or even prevent breast cancer becoming resistant to hormone therapy.
News items from 2019
New study on anastrazole treatment which reduces risk of breast cancer
13 Dec 2019
Ground-breaking research has found that the drug, anastrozole, continues to reduce the risk of breast cancer, even 10 years after initial treatment.
Drugs commonly used to treat arthritis may help to prevent breast cancer spreading to the bone, where it is incurable.
20 Nov 2019
In a new study published in Nature Communications, Manchester Breast Centre scientists Rob Clarke and Rachel Eyre demonstrate that NHS arthritis drugs anakinra, canakinumab and sulfasalazine could in future be repurposed to help treat breast cancer, following the discovery of the role of bone marrow in the spread of the disease to the bone.
Elke van Veen: Postgraduate Student of the Year
02 Jul 2019
Elke van Veen has won the prestigious Postgraduate Student of the Year award at this year’s Manchester Doctoral Excellence Awards.
PROCAS: revolutionising the breast screening process
11 Jun 2019
Women who are screened for breast cancer will receive greater tailored preventative intervention following the advancements of Prevent Breast Cancer’s PROCAS study, led by Professor Gareth Evans.
New research improves risk prediction, prevention and treatment of breast cancer
08 Jun 2019
Women screened for breast cancer could be given greater information on how likely they are to develop breast cancer, possible treatments to reduce their risk, and if it did develop, how likely it will respond to different treatments, according to new research.
Manchester team plays major part in pioneering research into breast cancer treatment
05 Jun 2019
Study reveals combining standard treatment with investigational therapy may extend life by up to six months.
Archived News Items
Manchester scientists given funding to research how to stop breast cancer spreading to bone
13 Oct 2017
University of Manchester scientist Dr Robert Clarke was given the grant by Breast Cancer Now on Secondary Breast Cancer Awareness Day and will use the grant of more than £195,000 for his research on breast cancer stem cells (BCSCs)
New test set to transform breast cancer prevention
09 Oct 2017
Women who have a family history of breast cancer are set to benefit from a new genetic test at Manchester University NHS Foundation Trust
Manchester scientist to study how ‘hibernating’ breast cancer cells evade treatment
12 Jul 2017
A leading Manchester scientist has been awarded a grant worth over £185,000 by Breast Cancer Now to investigate how breast cancer cells are able to hibernate for years before returning elsewhere in the body.
Inbuilt Body Clocks Link Breast Stiffness to Cancer Risks
31 Jan 2017
University of Manchester biologists have discovered that breast tissues have 24-hour body clocks, and that several hundred genes are regulated in a daily cycle.
University of Manchester Minute Lectures Series
04 Jul 2016
Take a look at the work being done in our Manchester Breast Centre affiliated labs
Could 5:2 diet play a role in preventing breast cancer?
17 Jun 2016
"Women who follow the 5:2 diet 'could reduce their risk of breast cancer','' the Mail Online reports.
Artist joins forces with Manchester Breast Centre to create new project to support breast cancer
08 Apr 2016
A Wilmslow artist has created a new project which she hopes will empower those battling breast cancer.
Combination of lapatinib and trastuzumab shrinks HER2 positive breast cancer significantly in 11 days after diagnosis
11 Mar 2016
Approximately a quarter of women with HER2 positive breast cancer, who were treated with a combination of the targeted drugs lapatinib and trastuzumab before surgery and chemotherapy, saw their tumours shrink significantly or even disappear, according to results from a Manchester-led trial.
Delving deeper into breast density
03 Mar 2016
Researchers in Manchester have been exploring the causes of high breast density – a known risk factor for breast cancer – that could reveal new ways to prevent the disease.
Breast screening recommendation for women with cancer-causing syndrome
07 Dec 2015
Researchers in Manchester have found that women with an inherited genetic syndrome are at increased risk of developing breast cancer and should be considered for earlier screening.
Manchester breast cancer clinic attributes increased uptake of double mastectomies to Angelina Jolie effect
24 Nov 2015
Researchers at a breast cancer prevention clinic in Manchester have observed an increased uptake of preventative double mastectomies since May 2013, when Angelina Jolie announced that she had undergone the procedure.
Cancer scientist appointed by President Obama visits Manchester
24 Oct 2015
Professor Max Wicha a leading breast cancer specialist from the University of Michigan, has been at The University of Manchester to discuss collaborations and deliver a keynote address to scientists.
Developing a gel that mimics human breast for cancer research
07 Oct 2015
Scientists at the Universities of Manchester and Nottingham have been funded to develop a gel that will match many of the biological structures of human breast tissue, to advance cancer research and reduce animal testing.
New approach found to tackle breast cancer hormone therapy resistance
17 Sep 2015
University of Manchester researchers funded by Breast Cancer Now have discovered a new explanation as to why women with oestrogen receptor positive (ER+) breast cancer develop resistance to hormone treatment, and a potential new approach to overcome the problem.
New drug combination shows promise for breaking breast cancer resistance
20 Apr 2015
Researchers from The University of Manchester working with drug development company Evgen Pharma, have developed a new combination of drugs which could overcome treatment resistance and relapse in breast cancer.
Potential for prediction of progression for early form of breast cancer
15 Apr 2015
Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.
Researchers identify new ways to drain cancer’s ‘fuel tank’
25 Nov 2014
Scientists at The University of Manchester have discovered a potential weakness in cancer’s ability to return or become resistant to treatment, by targeting the ‘fuel’ part of stem cells which allows tumours to grow.
28 September 2021
Individual Risk Assessment for patients with DCIS, lessons learned from the Ontario DCIS Cohort
Sue Astley & Cliona Kirwan
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