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Breast cancer research activities are located across Manchester and the MBC acts as an umbrella organisation for both clinicians and non-clinicians specialising in this area. Collaboration is key to the success of the MBC and its research.

Since the amalgamation of the key breast research groups in Manchester in 2005, the MBC has continued to develop and expand. The centre is now sited in four major organisations in Manchester: The Nightingale Centre and Genesis Prevention Centre at University Hospital of South Manchester NHS Foundation Trust, The Christie NHS Foundation Trust, The Breast Cancer Now Research Unit, Division of Molecular and Clinical Cancer Sciences and Faculty of Life Sciences at The University of Manchester and St Mary’s Hospital at Central Manchester University Hospitals NHS Foundation Trust. There are also scientists and clinicians based at a number of other locations across Greater Manchester.

Prevent Breast Cancer

The Nightingale and Genesis Prevention Centre is a £2 million state of the art research and screening centre, based at University Hospital South Manchester (UHSM) in Wythenshawe. It is a world class facility leading the way in breast cancer early diagnosis, prediction and prevention research.

Europe’s first purpose built breast cancer prevention centre, it contains specially designed consultation, examination, counselling, mammography, radiology and ultrasound rooms. There are also rooms dedicated to pathology, prosthesis, lymphodema and bone densitometry. As well as this, it provides training facilities aimed at addressing the shortage of breast cancer specialists and houses many researchers looking at ways to predict and prevent breast cancer.

Breast Cancer Now Research Unit

As an integral part of the Manchester Breast Centre, the Breast Cancer Now Research Unit, which is based in the Division of Molecular and Clinical Cancer Sciences at The University of Manchester, is directed by Dr Rob Clarke. In addition there are three Clinical Associates: Professor Nigel Bundred, Dr Sacha Howell and Professor Tony Howell. The Unit opened in 2008. In September 2016, Rob Clarke was appointed as the new Director of the Unit. Previous directors include Professor Tony Howell.

The objective of the Unit is to improve treatment and prevention of breast cancer. The Unit's research goals are to delineate breast epithelial cell behaviour within its tissue context and to determine how the breakdown of normal cell interactions with the local environment result in perturbed tissue organisation, proliferation, and survival of early breast cancers and its metastasis. This information aims to predict patients that will develop breast cancer and identify those who will become resistant to therapy and recur. It also aims to identify new therapeutic targets for both the prevention and treatment of the disease.

For more information on Breast Cancer Now, please see this link


Date:  31 October 201916:00
Speaker:  Karin de Visser
From:  NKI, Amsterdam, The Netherlands
Title:  Impact of the immune system on metastatic breast cancer and therapy response
Host:  Rob Clarke
Date:  07 November 201916:00
Speaker:  Cristina Branco
From:  Queen's University Belfast
Title:  TBA
Host:  Ahmet Ucar
Date:  12 December 201916:00
Speaker:  Charlotte Coles
From:  University of Cambridge
Title:  Translational research in breast cancer radiotherapy
Host:  Cliona Kirwan